Physico-chemical and biological properties landomycin E and its cultural production STREPTOMYCES GLOBISPORUS 3-1 [text] Abstract. Thesis ... candidate. Biol. Sciences: 03.00.07 / AV Tymchyk; Institute of Microbiology and Virology. DC Zabolotnoho NAS of Ukraine. - K., 2006. - 22 p.

Тимчик, Олеся Володимирівна (2006) Physico-chemical and biological properties landomycin E and its cultural production STREPTOMYCES GLOBISPORUS 3-1 [text] Abstract. Thesis ... candidate. Biol. Sciences: 03.00.07 / AV Tymchyk; Institute of Microbiology and Virology. DC Zabolotnoho NAS of Ukraine. - K., 2006. - 22 p. PhD thesis, Інститут мікробіології та вірусології імені Д.К. Заболотного.

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Abstract

Established that the long-term cultivation of strain 3-1 producer landomycin E on soy medium and ethanol storage solutions landomycin E molecule ostannoho dehidratuyetsya and converted into a compound purple with altered physical and chemical properties - maximum absorption and chromatographic mobility. Native form landomycin E shows higher antibiotic activity to gram-positive bacteria. LD50 for antibiotic laboratory mice and rats is 75 mg / kg animals. Landomycins E exhibits weak mutagenic activity in terms metabolitnoyi activation in S. typhimurium strains TA98 and TA100. The high sensitivity of the strain mycelium and spores of strain 3-1 Spo1 to lethal action of streptomycin

Item Type: Thesis (PhD)
Uncontrolled Keywords: S. typhimurium TA98 and TA100; streptomycetes; Spo1; streptomycin; landomycins E; toxicity, mutagenicity
Subjects: Abstracts > Спецради у інших ВНЗ
Divisions: Institutes > Institute of human > Chair of Anatomy and Physiology of a Human Being
Depositing User: Олеся Володимирівна Тимчик
Date Deposited: 04 Mar 2015 09:04
Last Modified: 02 Dec 2015 08:46
URI: http://elibrary.kubg.edu.ua/id/eprint/7269

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